Pavlovian-to-instrumental-transfer in Anorexia Nervosa : A pilot-study on conditioned learning and instrumental responding to low- and high-calorie food stimuli





Faculty/Professorship: Clinical Psychology and Psychotherapy  
Author(s): Vogel, Verena; Dittrich, Marie; Horndasch, Stefanie; Kratz, Oliver; Moll, Gunther H.; Erim, Yesim; Paslakis, Georgios ; Rauh, Elisabeth; Steins-Löber, Sabine  
Title of the Journal: European Journal of Neuroscience
ISSN: 0953-816X, 1460-9568
Corporate Body: European Neuroscience Association
Publisher Information: Oxford [u.a.] : Wiley
Year of publication: 2020
Volume: 51
Issue: 8
Pages: 1794-1805
Language(s): English
DOI: 10.1111/ejn.14592
URL: https://onlinelibrary.wiley.com/doi/full/10.111...
Abstract: 
Anorexia Nervosa is characterized by persistent restraint eating despite severe negative consequences and often a chronic course of the disease. Recent theoretical models suggest that abnormalities in reward processing and incentive salience of disorder-compatible stimuli as observed in addictive behaviours contribute to the development and maintenance of Anorexia Nervosa. The aim of the present study was to investigate the process of the acquisition of food-related conditioned responses and the influence of conditioned low-calorie and high-calorie food stimuli on instrumental responding for different foods. A Pavlovian-to-instrumental transfer paradigm and questionnaires on eating disorder psychopathology (EDE-Q, EDI-2) were administered to patients with Anorexia Nervosa (n = 39) and healthy controls (n = 41). Results indicated that patients with Anorexia Nervosa showed deficits of the acquisition of knowledge of the experimental contingencies. Nevertheless, in patients with Anorexia Nervosa and healthy controls instrumental responding for low- and high-calorie food rewards was affected by stimuli conditioned to these rewards; no group differences were observed. Importantly, in Anorexia Nervosa, instrumental responding for low-calorie food increased with increasing severity of eating disorder psychopathology suggesting weight-loss directed behaviour. Future studies are warranted to enhance our understanding of deficits of reward-associated learning and to replicate and extend findings with regard to the impact of conditioned stimuli on instrumental responding. At present, our findings suggest that cognitive treatment interventions might be warranted that challenge dysfunctional beliefs about weight loss.
GND Keywords: Anorexia nervosa; Appetit; Konditionierung
Keywords: appetitive conditioning, eating disorders, goal-directed behaviour, instrumental responding, PIT effect
DDC Classification: 150 Psychology  
RVK Classification: CU 3400   
Peer Reviewed: Ja
International Distribution: Ja
Type: Article
URI: https://fis.uni-bamberg.de/handle/uniba/48348
Release Date: 29. July 2020