Integrated personalized diabetes management improves glycemic control in patients with insulin-treated type 2 diabetes: Results of the PDM-ProValue study program

Professorship/Faculty: Lehrstuhl für Klinische Psychologie/Psychotherapie
Author(s): Kulzer, Bernhard ; Daenschel, Wilfried; Daenschel, Ingrid; Schramm, Wendelin; Messinger, Diethelm; Weissmann, Joerg; Vesper, Iris; Parkin, Christopher G.; Heinemann, Lutz
Pages / Size: 200-212
Title of the Journal: Diabetes research and clinical practice : the official journal of the International Diabetes Federation
Language(s): English
ISSN: 0168-8227
Publisher Information: Amsterdam [u.a.]
Issue: 144 (2018)
Publisher Information: Elsevier
Year of publication: 2018

Globally, many patients with insulin-treated type-2 diabetes are suboptimally controlled. The PDM-ProValue study program evaluated whether integrated personalized diabetes management (iPDM) has the potential to improve clinical outcomes.

101 practices with 907 patients participated in the 12-month, prospective, controlled, cluster-randomized study program. HbA1c levels, therapy changes, frequency of hypoglycemic episodes, patient reported outcomes, and physician satisfaction were assessed.

iPDM led to a greater reduction in HbA1c after 12 months vs. usual care (−0.5%, p < 0.0001 vs. −0.3%, p < 0.0001), (Diff. 0.2%, p = 0.0324). Most of the HbA1c reduction occurred after 3 months and remained stable thereafter. The percentage of patients with therapy adjustments was higher in the iPDM group at all visits (p < 0.01 at week 3, month 3, month 6). Patient adherence at month 12 was higher in the iPDM group compared to baseline (Odds ratio = 2.39; p = 0.0003); also, patient treatment satisfaction (DTSQc: 12.2 vs. 10.4, δ = 1.78, p = 0.004; DTSQs: 31.0 vs. 30.0, δ = 0.924, p = 0.02), and physician satisfaction was higher in the intervention group.

iPDM improved the use of diagnostic data leading to better glycemic control, more timely treatment adjustments (indicating reduced clinical inertia), and increased patient adherence and treatment satisfaction among patients and physicians.
Keywords: Diabetes management, SMBG, Type 2 diabetes, Personalized diabetes therapy, Digital tools
DOI: 10.1016/j.diabres.2018.09.002
Peer Reviewed: Ja
International Distribution: Ja
Document Type: Article
Release date: 17. August 2019

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