Efficacy of an education and treatment programme for people with type 2 diabetes on a non-intensive insulin regimen (MEDIAS2 BOT+SIT+CT): results of a RCT

Professorship/Faculty: Lehrstuhl für Klinische Psychologie/Psychotherapie ; Professur für Pathopsychologie 
Author(s): Hermanns, Norbert ; Maier, Berthold; Schall, Sabine; Haak, Thomas; Kulzer, Bernd
Pages / Size: 1 pdf-Datei (1 S.)
Language(s): English
Corporate Body: 52nd EASD Annual Meeting, 12 - 16 Sept 2016, Munich, Germany
Publisher Information: Bamberg : OPUS
Year of publication: 2017
Source/Other editions: Ursprünglich in: Diabetologia : journal of the European Association for the Study of Diabetes (EASD) 59 (2016) Suppl 1, S425 (884-P)
Year of first publication: 2016
Background and aims: MEDIAS2 BOT+SIT+CT (More Diabetes Selfmanagement for People with type 2 diabetes on a Basal insulin supported Oral Therapy or on Supplementary Insulin Treatment with prandial insulin or Conventional Insulin Treatment with biphasic insulin) is a newly developed diabetes education and treatment programme for people with type 2 diabetes(PWD-T2) on a non-intensive insulin treatment regimen. The development of MEDIAS2 BOT+SIT+CT was based on self-management and empowerment theory. The efficacy of the newly developed intervention MEDIAS 2 BOT+SIT+CT (IG) was evaluated in a randomized trial with a six month follow-up period. The control group (CG) participated in an established education programme (Treatment- and education programme for type 2 diabetic patients with injection of prandial and/or basal insulin). The primary outcome of this study was the reduction of HbA1c. Materials and methods: Both interventions in IG and CG consisted of 6 lessons. At baseline and follow-up the HbA1c was measured in a central laboratory. Participants also completed questionnaires to measure diabetes distress, empowerment, diabetes knowledge and hypoglycaemia awareness. Results: 186 PWD-T2 participated in the study (IG vs. CG: age 63.0 ±8.4 vs. 63.2 ±7.6 yrs.; diabetes duration 11.5 ±5.7 vs. 11.4 ±7.0 yrs.; duration of insulin treatment 3.6 ±4.0 vs. 3.6 ±4.5 yrs.; HbA1c 8.0 ±1.3 vs. 7.9 ±1.2 %; respectively 63.9 ± 14.2 mmol/mol vs. 62.8 ± 13.1 mmol/mol; hypoglycaemia-unawareness score 2.0 ±1.0 vs. 2.1 ±0.9). There were no significant differences at baseline between IG and CG. HbA1c was significantly more reduced in IG compared to CG (-0.7 ±0.1 vs. -0.3 ±0.1 percentage Points, respectively -7.7 ±1.1 mmol/mol vs. 4.4 ±1.1 mmol/mol; p=.02). Hypoglycaemia awareness did not deteriorate in both groups (1.9 ±0.1 vs. 2.1 ±0.1 p=.276). Diabetes distress and empowerment improved in both groups, but there were no significant between group differences. Conclusion: Participation in the newly developed MEDIAS2 BOT+SIT+CT treatment and education programme led to a significant improvement of glycaemic control without a measurable increase in risk for hypoglycaemia. An important component of the newly developed MEDIAS2 BOT+SIT+CT was self-titration of insulin doses; this might have contributed to the positive impact of this programme on glycaemic control. In summary, MEDIAS2 BOT+SIT+CT has been proven as an effective treatment and education tool.
URL: http://www.easdvirtualmeeting.org/resources/efficacy-of-an-education-and-treatment-programme-for-people-with-type-2-diabetes-on-a-non-intensive-insulin-regimen-medias2-bot-sit-ct-results-of-a-rct
URN: urn:nbn:de:bvb:473-opus4-496851
Peer Reviewed: Ja
International Distribution: Ja
Document Type: Other
URI: https://fis.uni-bamberg.de/handle/uniba/42200
Release date: 24. July 2017

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