Different associations of depressive subtypes with glycemic control.

Professorship/Faculty: Clinical Psychology and Psychotherapy  
Authors: Ehrmann, Dominic; Hermanns, Norbert ; Schmitt, Andreas; Haak, Thomas; Kulzer, Bernhard
Publisher Information: Bamberg : OPUS
Year of publication: 2016
Pages / Size: 1 pdf-Datei (1 S.)
Source/Other editions: Ursprünglich in: Diabetes : the journal of the American Diabetes Association 64 (2015) Supplement 1, A218-A219
Year of first publication: 2015
Language(s): English
Licence: German Act on Copyright 
URN: urn:nbn:de:bvb:473-opus4-464165
Document Type: Other
Association of depression with glycemic control are not conclusive. While
some studies found a positive association, others found none or found that
diabetes distress is a mediating factor. These inconsistencies might be
due to the complex symptomatology of depression. Depressive symptoms
can range from sleep or appetite disorders to depressed mood and having
crying spells. Thus, depressive symptoms can be divided into somatic and
affective symptoms. This study investigated the associations of the different
depressive subtypes with glycemic control. 923 patients completed the
Center for Epidemiological Studies - Depression scale (CES-D) which offers
subscales for somatic and affective symptoms. Linear regression analysis
with HbA1c as dependent variable was conducted. Independent variables of
interest were the somatic and affective scores of the CES-D controlled for
demographic (age, gender, body mass index, education) and medical (diabetes
type, diabetes duration, number of SMBG, late-complications) variables
as well as diabetes distress. Both depressive subtypes were signifi cantly
associated with HbA1c. A greater somatic symptomatology was associated
with a higher HbA1c (β = .15; p = .001) whereas a greater affective symp-
For author disclosure information, see page A810.
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tomatology was associated with a lower HbA1c (β = -.15; p = .001). Greater
diabetes distress was associated with higher HbA1c (β = .13; p = .001). Linear
regression with depressive symptoms in general (CES-D total score) as independent
variable revealed no signifi cant association (β = -.01; p = .86). This
study demonstrated that depression is a complex condition and offers an explanation
for the inconsistencies in current literature regarding associations
with glycemic control. Only the differentiation of subtypes offered a more
complete picture of the associations of depression with glycemic control.
In clinical practice and further research, a closer look which symptoms of
depression are present may be helpful to better understand depression as
a vulnerability factor.
Peer Reviewed: Ja
International Distribution: Ja
URI: https://fis.uni-bamberg.de/handle/uniba/40286
Release Date: 22. March 2016

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