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Is Diabetes Related Distress a Risk Factor for Depression in Diabetes?
Hermanns, Norbert; Kulzer, Bernhard; Haak, Thomas (2012): „Is Diabetes Related Distress a Risk Factor for Depression in Diabetes?“.
Faculty/Professorship:
Author:
Title of the Journal:
Diabetes : the journal of the American Diabetes Association
ISSN:
1939-327X
Corporate Body:
ADA 72nd Scientific Sessions, 08.-12. June 2012, Philadelphia, Pennsylvania
Year of publication:
2012
Volume:
61
Issue:
Suppl. 1
Pages:
Language:
English
Abstract:
Introduction: Recent meta-analysis showed that diabetes seems to be a risk factor for incident depression. This prospective study examines the role of elevated diabetes distress on the persistence or the recovery from elevated depressive symptoms at a 6-month follow-up.Methods: Participants completed the CES-D. A score of >=16 indicate elevated depressive symptoms. The Problem Areas in Diabetes Scale (PAID) assessed diabetes related distress; a PAID score of >=30 indicate moderate diabetes related distress. Logistic regression models were performed. Persistence and recovery from elevated depressive symptoms were the dependent variables. The independent variable was diabetes related distress. The models were adjusted for potential demographic (age, gender) or medial confounders (BMI, diabetes duration, A1C, diabetes type and late complications).Results: 351 diabetic patients were included (age 50,8 ±11.4 yrs, 52% female, 58% type 2 diabetic patients, diabetes duration 12.9 ±11.1 yrs, BMI 29,9 ±6,9 kg/m², A1c 7.9 ±1.5%). At baseline 125 patients (35.6%) reported elevated depressive symptoms. At follow up 96 patients (27.3%) still had an elevated depression score. If diabetes related distress was present at baseline the hazard ratio of having persistent elevated depressive symptoms at follow up was 6.67 (95% CI 3.79 - 11.72). Adjusting for confounding variables did not change the hazard ratio substantially (HR 6.02 95% CI 3.32 - 10.89). In addition the chance for recovery from elevated depressive symptoms was significantly reduced if diabetes related distress was present (Odds ratio 0.37 95% CI 0.17 - 0.77). Controlling for possible confounders did not change the odds ratio (0.36 95% CI 0.16 - 0.82).Conclusion: Diabetes related distress seems to play a decisive role for an unfavorable course of depressive symptoms. Diabetes related distress may be a mediating factor between diabetes and depression. Addressing diabetes related distress may be able to ameliorate depression in people with diabetes.
Type:
Article
published:
February 11, 2016
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https://fis.uni-bamberg.de/handle/uniba/40190