This chapter focuses on the unique features of Juliana Claassens’ theological work within the historical, socio cultural, economic and religious context that motivated her approaches. It follows the trajectory of Claassens’ theological thinking and how she has been able to navigate various issues of discrimination and prejudice that stem from patriarchy, colonialism, capitalism, racism, tribalism, sexuality and disability, among other social factors, using diverse sources that include novels, films and music, besides Scriptures. In addition, the essay investigates how Claassens’ work has dialogued with other theologies, specifically African male theologies, Global South theologies, and Western feminist theologians. The conclusion highlights Claassens’ main contributions to the world of knowledge and liberation as well as its potential applications to the future world and work.