The term NeuroIS appears more frequently within the field of information system (IS). NeuroIS describes the idea of applying cognitive neuroscience theories, methods, and tools to obtain physiological responses of the user while using IS. However, before adopting these methods into IS research, a proper assessment is necessary to determine whether the methods used in other disciplines are also applicable to IS research. The present research introduces the method of measuring the electrodermal activity (EDA). Thereby, the physiology and different measurement parameters are described. By identifying the use of EDA within other disciplines, the present research reveals application areas for EDA in six different research streams in IS research and poses further research questions, which might be answer by applying EDA in these areas.