This article reviews the body of empirical work on human resource management in times of crisis, including that which was conducted prior to the COVID-19 pandemic and that which has been published since the outbreak of the COVID-19 pandemic. Following this, we introduce the special issue, summarizing the six articles included. Finally, we present a comprehensive agenda for future research on how to manage human resources during times of crisis based on the insights from the review and our own knowledge of the literature.