Mk 8:22-26 remains one of the two micro-narratives in the synoptic gospels where Jesus applied spittle in healing someone. The man, being healed, was blind. Although Jesus had to apply a second level of healing before the blind man could be healed properly, this incident indicates that Jesus could heal diseases and sickness through other means other than words of mouth. This is some form of encouragement for the use of medicine in curing diseases and sicknesses among Christians. Since the outbreak of COVID-19 pandemic in the world and the subsequent rolling out of its vaccine, it seems that the pandemic has been contained to some point. However, the level of receptiveness of the vaccine among Nigerians has been problematic. This has given rise to what is generally termed COVID-19 vaccine hesitancy among Nigerians of which Christians form a large percentage. Using the historical-critical approach to exegesis, with oral interview serving as a means of data collection, this work studied the micro-narrative of Mk 8:22-26 to relate how it can encourage Christians in Nigeria to be more receptive of COVID-19 vaccine. Findings in the study indicate that by healing a blind man with spittle, a well-known medical practice of the time, Jesus accepts medical processes involved in curing diseases. This means that Christians in Nigeria are encouraged to be receptive of COVID-19 vaccine as a means of preventing COVID-19 related health issues and/or COVID-19 related deaths. It also calls for the re-evaluation of Nigerian Christians’ stance on Faith (Religion)–COVID-19 vaccine debate.